Enema for Ulcerative Colitis: getting the most out of
What is Ulcerative Colitis?
Ulcerative Colitis (UC) is a lifelong condition that causes inflammation and ulceration
of the inner lining of the colon (the large bowel) and rectum (the lowest part of the
large bowel). In UC, ulcers develop on the lining of the colon and these may bleed and
produce pus. The inflammation usually begins in the rectum and lower colon, but it
may affect the entire colon. If colitis only affects the rectum, it is called proctitis.
UC is generally categorised according to how much of the colon is affected:
Proctitis Proctosigmoiditis
Left-sided or distal colitis
Total or pancolitis
What symptoms can I expect to experience?
The main symptoms include:
l Diarrhoea
l Abdominal pain
l Rectal bleeding
Extreme tiredness
Feeling generally unwell
l Loss of appetite and weight
l l
your treatment
Why is it important to use your PENTASA enema?
You have been prescribed PENTASA enema for the treatment of your UC. Your
PENTASA enema contains the anti-inflammatory active ingredient called mesalazine,
also known as 5-ASA.
People with life-long diseases, such as UC, may not always take their medicines as
instructed by their IBD Team. This is possibly due to embarrassment or concerns of
side effects or of the potential discomfort of using an enema.
However, many studies have proven that
using your enema, as prescribed by your
IBD Team, plays an important role in
achieving and maintaining remission
in mild to moderate UC. 1
The PENTASA enema’s
100 mL liquid helps reach
more of the colon, allowing
the active ingredient to
act locally and reduce
the inflammation where
it is needed most. 2
of patients who used both an enema coupled with
oral therapy achieved mucosal healing compared
with 83% of patients receiving just oral therapy. 3